Anna Radke

Radke Fall 2016


Contact Information

112 Psychology Building
Miami University
Oxford, OH 45056
External Website- www.aradlab.com

Education

Postdoctoral Fellowship, National Institutes of Health 2012-2016
PhD, University of Minnesota, 2011
BA, St. Olaf College, 2006

Teaching Interests

Biopsychology, Psychopharmacology, Neuroscience

Research Interests

In the Reward and Addictive Disorders (RAD) Lab we use animal models to study motivational brain circuits on a systems level. Our goal is to understand how these neural circuits function in a healthy state as well as to uncover adaptations that contribute to maladaptive behaviors such as addiction.  Currently we are investigating glutamatergic and dopaminergic contributions to compulsive-like behaviors such as inflexible alcohol drinking in mice.  Our principle experimental approaches include manipulating behavior with pharamacological, genetic, and chemogenetic tools and measuring changes in dopamine release with fast scan cyclic voltammetry. 

Professional Recognition

  • Postdoctoral Mentor Award, National Institutes of Health (2013, 2014, 2015)

  • NIDA Predoctoral Training Grant in Pharmaconeuroimmunology, University of Minnesota (2010-2011)       

  • NICHD Predoctoral Training Grant in Cognitive Sciences, University of Minnesota (2007-2010)

  • Charles and Dorothy Bird Award for outstanding research, Sigma Xi, University of Minnesota (2009) 

Representative Publications

Radke AK, Jury NJ, Delpire E, Nakazawa K, Holmes A. (2017). Reduced ethanol drinking following selective cortical interneuron deletion of the GluN2B NMDA receptor subunit. Alcohol 58:47-51.

Radke AK, Jury NJ, Kocharian AK, Marcinkiewcz CA, Lowery-Gionta EG, Pleil KE, McElligot ZA, McKlveen JM, Kash TL, Holmes A. (2017). Chronic EtOH effects on putative measures of compulsive behavior in mice. Addiction Biology 22:423-434.

Brigman J, Izquirdo A, Radke AK, & Holmes A. (2017). The neural basis of reversal learning: An updated perspective. Neuroscience 345:12-26

Radke AK, Nakazawa K, Holmes A. (2015). Cortical GluN2B deletion attenuates punished suppression of food reward-seeking.Psychopharmacology 232: 3753-3761.

Radke AK, Pickens CL, Holmes A. (2014). The effects of stress on measures of alcohol drinking in rodents. In: Noronha ABC, Cui C, Harris RA, and Crabbe JC (eds.) Neurobiology of Alcohol Dependence, pp. 97-110 Oxford: Academic Press.

A complete list of publications can be found here: https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/50960248/?sort=date&direction=descending

Courses Taught

251 Introduction to Biopsychology
410A Capstone in Neuroscience
456/556 Biological Bases of Behavior

Research Lab Information

Undergraduate students interested in joining the Reward and Addictive Disorders lab should fill out an application here: www.aradlab.com/contact.

Interested graduate students should contact Dr. Radke directly.