Jon Fritz, Ph.D.
Contact Info
Education
- Ph.D. Biophysics with a specialization in Biomedical, Clinical, & Translational Science, The Ohio State University (2026)
- M.S. Biophysics, The Ohio State University (2023)
- B.A. Physics, Carnegie Mellon University (2020)
Research Interests
- Organ-on-a-chip
- Cellular mechanobiology
- Computational fluid dynamics
- Pulmonary disease & dysfunction
Biography
Jon Fritz, Ph.D. is a visiting assistant professor in the Dept. of Chemical, Paper, and Biomedical Engineering at Miami University. After completing a B.A. in Physics at Carnegie Mellon University, Dr. Fritz earned his Ph,D, in Biophysics under the mentorship of Samir Ghadiali, Ph.D. and Joshua Englert, M.D. at the Ohio State University. During his graduate work, he utilized techniques in biophysical modeling, molecular biology, and microfluidics to characterize mechanisms of ventilator-induced lung injury. In addition to cross-disciplinary research interests, Dr. Fritz enjoys teaching courses that span science, medicine, and engineering.
Courses Taught
- CEC 111 Imagination, Ingenuity and Impact I
- CPB 219 Statics & Mechanics of Materials
Publications
- Fritz, J.R., Englert, J.A., Ghadiali, S.N. A multiscale model for extracting biophysical parameters of lung surfactant function under oscillating volume conditions. Journal of Colloids and Interface Science. In review. 2026
- Bentley, I.D., Fritz, J.R., Kapoor, A., Hite, R.D., Ghadiali, S.N., Englert, J.A. Annexin A2 regulates surfactant dysfunction during injurious ventilation. bioRxiv. 2026
- Karpurapu, M., Yan, J., Chung, S., Posham, L., Fritz, J.R., Englert, J.A., Pannu, S.R., Parinandi, N., Berdyshev, E., Zhang, L., Christman, J.W. Specialized pro-resolving mediator loaded extracellular vesicles mitigate pulmonary inflammation. Am. J. Respir. Cell Mol. Bio. 2025
- Salavatian, S., Wong, B., Kuwabara, Y., Fritz, J.R., Varghese, C.G., Howard-Quijano, K., Armour, J.A., Foreman, R.D., Ardell, J.L., Mahajan, A. Comparing the memoary effects of 50-Hz lowfrequency and 10kHz high-frequency thoracic spinal cord stimulation on spinal neural network in a myocardial infarction porcine model. Neuromodulation: Technology at the Neural Interface. 27(7):1177-1186. 2024
- Salavatian, S., Kuwabara, Y., Wong, B., Fritz, J.R., Howard-Quijano, K., Foreman, R.D., Armour, J.A., Ardell, J.L., Mahajan, A. Spinal neuromodulation mitigates myocardial ischemiainduced sympathoexcitation by suppressing the intermediolateral nucleus hyperactivity and spinal neural synchrony. Frontiers in Neuroscience. 17(1180294). 2023
- Fritz, J.R., Loney, R.W., Hall, S.B., Tristram-Nagle, S.A. Suppression of Lα/Lβ phase coexistence in the lipids of pulmonary surfactant. Biophys. J. 120(2):243-253. 2021
- Loney, R.W., Brandner, B., Dagan, M.P, Smith, P.N., Roche, M., Fritz, J.R., Hall, S.B., TristramNagle, S.A. Changes in membrane elasticity caused by the hydrophobic surfactant proteins correlate poorly with adsorption of lipid vesicles. Soft matter. 17(12):3358-3366. 2021
- Loney, R.W., Panzuela, S., Chen, J., Yang, Z., Fritz, J.R., Dell, Z., Corradi, V., Kumar, K.,
Tieleman, P.D., Hall, S.B., and Tristram-Nagle, S.A. Location of the hydrophobic surfactant
proteins, SP-B and SP-C, in fluid-phase bilayers. J. Phys. Chem. B. 124(31):6763-6774. 2020