Paul T. Reidy, Ph.D., FACSM

Educational Credentials

• Post-Doctoral Fellow, Drummond Laboratory, University of Utah
• Ph.D., Biomedical Science-Rehabilitation Science, University of Texas Medical Branch
• MS., Exercise Physiology Human Performance Laboratory, Ball State University
• B.A., Exercise Science, Anderson University

Professional Memberships/Honors

• Fellow of the American College of Sports Medicine (FACSM), 2026 – Present

Meet Your Professor

Courses Taught

• KNH 101 Personal Nutrition
• KNH 188 Physical Activity and Health
• KNH 188H Physical Activity and Health - Honors Section
• KNH 102 Fundamentals of Nutrition
• KNH 409/509 Sport Nutrition
• KNH 468/568 Physiology of Exercise and Physical Activity
• KNH 621 Research Foundations in Kinesiology, Nutrition, and Health

Scholarly Interests

I have two areas of inquiry that revolve around the impact of physical activity on metabolism and skeletal muscle size and function. Also, I collaborate with several other faculty, some of whom (Kyle Timmerman, Ph.D., and Kevin Ballard, Ph.D., among others) I share wet lab space with. Additionally, I collaborate with several faculty members in the Center of Integrative Metabolism.

One of these areas is clinical research (research involving human subjects). With clinical research, I am using the model of step reduction (reduced activity) to examine how quickly the symptoms of diabetes (metabolic dysfunction) develop and how quickly they can recover following recovery (return to normal physical activity levels). I am especially interested in understanding how this happens in different populations (lean vs obese, men vs. women, healthy vs. pre-diabetic vs diabetic) and if immune cells are involved. Our KNH team has also examined how electric bikes could be used to improve glucose control. Additionally, I have an interest and history in examining protein sports nutrition, specifically concerning the skeletal muscle stem cells in young and older adults. I also use animal research, typically involving mice, to address another question regarding physical inactivity. I use a rodent model of physical inactivity (or muscle disuse) called hindlimb unloading to examine extreme and stressful physical inactivity like bedrest and hospitalization to cause muscle atrophy (muscle size loss) and then to examine recovery on muscle size. I also use a small mouse cage to test a more generalizable and less extreme form of physical inactivity. My particular interest is to examine how muscle disuse during early postnatal growth (a key period of childhood development) could impact muscle size and function during early and late adulthood.

Undergraduate and graduate students have been very active in all aspects of my research program. Students under my supervision have gained significant experience in laboratory techniques, study design, data acquisition, analysis, and presentation.

Service and Community Engagement

• Faculty Advisor for the Miami University Exercise is Medicine - On Campus Initiative.

What research experiences can students expect in my lab?

My research areas have some overlapping aspects that students CAN tap into.

Very few students will do ALL the below activities but rather have some exposure to a few of them.

• Clinical research: this will be starting in several months as I am in the process of receiving administrative approval and seeking more funding for this area of research
  • Involves
    • Clinical coordination (working with people)
    • Documentation of paperwork
    • Sample collection (blood draws)
    • Sample analysis of muscle samples
    • Data Analysis
    • Data presentation
    • Manuscript preparation
• Animal research: banked samples and future rodent experiments
  • Involves
    • Sample collection (rodent dissections)
    • Sample analysis of tissue samples (mostly muscle)
    • Data Analysis
    • Data presentation
    • Manuscript preparation

Very few students will do ALL the below activities but rather have some exposure to a few of them.

Laboratory work: Sample analysis of muscle samples

• Gene expression analysis
  • Muscle processing
    • Isolate RNA
    • Make copyDNA (reverse transcription)
    • Specific gene expression analysis with semi-quantitative Polymerase chain reaction (PCR)

• Immunohistochemistry/immunofluorescence
  • Muscle biopsy sample sectioning
    • Staining
    • Imaging of
    • Image processing
    • Image analysis

Recent Publications

I have a total of 59 peer-reviewed publications since 2010, 23 of which are 1st author. The average impact factor is 4.65. Since the inception of my position at Miami University in Fall 2019, I have contributed to the publication of 25 peer-reviewed scientific manuscripts, 21 abstracts, and 5 invited scientific presentations.

(†denotes work published/completed since hire date; *denotes Miami graduate student contributor; **denotes Miami undergraduate student contributor; #denotes equal contribution)

1. †Ruff Z, Miller MJ, Moro T, Reidy PT, Ebert SM, Adams C, Volpi E, Rasmussen BB. Resistance exercise training in older men reduces ATF4-activated and senescence-associated mRNAs in skeletal muscle. Geroscience. 2025 Jun;47(3):4601-4622. doi: 10.1007/s11357-025-01564-2.[2025 IF: 5.6; QR: 1 (Geriatrics and Gerontology); AR: ~20%, Contribution: 10%]
2. †Alessio HM, Ballard KD, Reidy PT, Hayward K, Bagg A**, Coley R**, Montoye AHK, Timmerman KL. Short-term e-bicycle riding results in favorable cardiometabolic shifts in moderately active adults. Eur J Appl Physiol. 2024 Jul;124(7):1969-1977. doi: 10.1007/s00421-024-05418-1. Epub 2024 Feb 1. PMID: 38300319; PMCID: PMC11199247.
3. †Petrocelli JJ, McKenzie AI, de Hart NMMP, Reidy PT, Mahmassani ZS, Keeble AR, Kaput KL, Wahl MP, Rondina MT, Marcus RL, Welt CK, Holland WL, Funai K, Fry CS, Drummond MJ. Disuse-induced muscle fibrosis, cellular senescence, and senescence-associated secretory phenotype in older adults are alleviated during re-ambulation with metformin pre-treatment. Aging Cell. 2023 Nov;22(11):e13936. doi: 10.1111/acel.13936. Epub 2023 Jul 24. PMID: 37486024; [2022 IF: 7.8; QR: 1 (Aging, Cell Biology); AR: 24%; Contribution: 10%; Citations: 56.
4. †Canter DJ**, Canter DJ**, Finucan TP**, Reidy PT, Timmerman KL. A comparison of energy expenditure and perceived exertion between standard axillary crutches, knee scooters, and a hands-free crutch. PM R. 2024 June. doi: 10.1002/pmrj.13109. PMID: 37950663. [2022 IF: 2.1; QR: 1 (Rehabilitation); AR: 21%; Contribution: 20%; Citations:2].
5. † Roberts MD, McCarthy JJ, Hornberger TA, Phillips SM, Mackey AL, Nader GA, Boppart MD, Kavazis AN, Reidy PT, Ogasawara R, Libardi CA, Ugrinowitsch C, Booth FW, Esser KA. Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions. Physiol Rev. 2023 Oct 1;103(4):2679-2757. doi: 10.1152/physrev.00039.2022. Epub 2023 Jun 29. Review. PubMed PMID: 37382939.
6. †Reidy PT, Borack MS, Dickinson JM, Carroll CC, Burd NA, Drummond MJ, Fry CS, Lambert BS, Gundermann DM, Glynn EL, Markofski MM, Timmerman KL, Moro T, Volpi E, Trappe S, Trappe TA, Harber MP, Rasmussen BB. Postabsorptive muscle protein synthesis is higher in outpatients as compared to inpatients. Am J Physiol Endocrinol Metab. 2023 Aug 1;325(2):E113-E118. doi: 10.1152/ajpendo.00144.2023. Epub 2023 Jun 14. PubMed PMID: 37315157; PubMed Central PMCID: PMC10393319.
7. †Alessio, HM, Timmerman, KL., Ballard, K, Reidy, PT., Bagg, A**., Montoye, AHK. Health and Environmental Benefits of Riding an Electric Bicycle. ACSM's Health and Fitness Journal
8. †Ferrara PJ, Reidy PT (co-first author), Petrocelli JJ, Yee EM, Fix DK, Mahmassani ZS, Montgomery JA, McKenzie AI, de Hart NMMP, Drummond MJ. Global deletion of CCL2 has adverse impacts on recovery of skeletal muscle fiber size and function and is muscle specific. J Appl Physiol (1985). 2023 Apr 1;134(4):923-932. doi: 10.1152/japplphysiol.00444.2022. Epub 2023 Mar 2. PMID: 36861669; PMCID: PMC10069960.
9. †Reidy PT, Smith AD*, Jevnikar BE**, Kachulkin A**, Williams, R**, Perlman E**, Schmidt R**, Doctor A**, Monnig J**, Mahmassani ZS, Fix D, McKenzie AI, Petrocelli JJ, de Hart NM, Drummond MJ. Muscle disuse as hindlimb unloading in early postnatal mice negatively impacts grip strength in adult mice: A pilot study. J Appl Physiol (1985). 2023 Apr 1;134(4):787-798. doi: 10.1152/japplphysiol.00681.2022. Epub 2023 Feb 9. PMID: 36759163; PMCID: PMC10042595.
10. †Doctor AK**, Monnig JM**, Kerr CN*, Bagg AM**, Pickering CE**, Reidy PT. Role of ingested amino acids/protein in the promotion of resistance exercise-training adaptations in aging: analysis of meta-analyses. Nutrition and Healthy Aging Preprint: 1–17, 2022. doi: 10.3233/NHA-220183

Book Chapters

Marcus R, Reidy P, LaStayo P. Impaired Muscle Performance in Older Adults. p. 365-78. In: Guccione's Geriatric Physical Therapy 4th Edition, 4th edition. 2020. Avers, D. & Wong, R.A. (Eds.). Elsevier, Amsterdam, The Netherlands.

Recent Grants

Internal

• †PI: The longitudinal effect of physical inactivity on immune health. Spring 2023 Miami University Faculty Research Grants Program. $34,483. (Funded).
• Mentor to 5 students who submitted URA proposal: Effects of Access to an Assistive Transportation Device (Scooter) on Measures of Physical Activity, Blood Flow and Metabolic Health. (Spring 2023) Miami University Undergraduate Research Committee. $1000 (Funded).
• †PI: External grant proposal development for examination of the impact of physical inactivity and recovery from physical inactivity of metabolic and vascular function with emphasis on age and health status. (Fall 2022 for Summer 2023) College of Education, Health, & Society Summer External Grant Proposal Development Awards. $6,000 (Funded).
• PI: Effect of assistive transportation device use on acute measures of health: Impact of weight and habitual physical activity level. (November 2022). College of Education, Health, & Society Research Seed Grant. $4,930 (Funded)
• †Co-PI: Does variation in metabolic rate drive change in atrophy rate? Miami University Cornerstone Grant Program - Advanced Research Teams $87,5700 (Unfunded).
• †PI: Effect of level of early life physical inactivity on muscle and metabolic health during development. College of Education, Health, & Society Summer Research Award. $6,000 (Funded). (Summer 2022). 

External

• Co-I: Interactive roles of cardiorespiratory fitness and adiposity on recovery of impaired glucose and vascular control after physical inactivity. National Institutes of Health $422,894. 1R15 HL177798-01 Feb 2024 – (Impact Score: 29, funded by the National Heart, Lung, and Blood Institute (NHLBI) April 18, 2025).
• PI: Influence of early life physical inactivity during a key period of postnatal development on adult muscle quality – from matrix to mortality. National Institutes of Health National Institute of Arthritis and Musculoskeletal and Skin Diseases. 1R15AR084182-01 $410,071. June 2023 – (Impact Score: 38 Percentile: 26 – Funded Sept 25, 2024).