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A76 - Investigating a role for ecdysteroid reception during nervous system reorganization in the fruit fly, Drosophila melanogaster
Ecdysteroid receptors (EcR) are proteins that receive hormonal signals to drive life-stage specific changes in neuronal development and reorganization of the nervous system.
A76 - Investigating a role for ecdysteroid reception during nervous system reorganization in the fruit fly, Drosophila melanogaster
Mentors: Joyce Fernandes, Ph.D., Jackson Riffe (Graduate Mentor)
Ecdysteroid receptors (EcR) are proteins that receive hormonal signals to drive life-stage specific changes in neuronal development and reorganization of the nervous system. In the fruit-fly, these proteins drive the four-day process of metamorphosis and are important for the resulting neural plasticity - for example re-organization of layers of glial cel
ls that surround abdominal nerves. Our project will test the hypothesis that EcR expressed by an external layer of glial cells (PG) initiates a signaling cascade that brings about degradation of an acellular layer, the Neural Lamella (NL).
