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C06 - Soleus and Taedl Myofiber Cross-Sectional Area Across a Range of Physical Inactivity in Early Postnatal Mice
It is well known that physical inactivity has a negative effect on health, partcularly that of the muscles.
C06 - Soleus and Taedl Myofiber Cross-Sectional Area Across a Range of Physical Inactivity in Early Postnatal Mice
Mentor: Paul Reidy, Ph.D.
It is well known that physical inactivity has a negative effect on health, partcularly that of the muscles. However, less is known about the effects of physical inactivity during early life on muscle development. The Soleus (SOL) and Tibialis Anterior/Extensor Digitorum Longus complex (TA/EDL) are leg muscles relevant for several basic motor functions, such as walking and would be impacted by early life inactivity. Both muscles contrast in size and fiber type composition.The purpose of this study is to examine how early life periods of varying activity and inactivity affect myofiber size and composition after a short, controlled treatment and post-treatment recovery period that encompasses a key period of development where significant growth occurs, in two different leg muscles.