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2025 Poster Session B
B48 - Investigating Animal Rotavirus Receptor Binding Domains Interactions with Human Receptors to Understand Zoonotic Potential
Understanding binding of animal rotavirus strains offers insight into zoonotic potential
2025 Poster Session B
B48 - Investigating Animal Rotavirus Receptor Binding Domains Interactions with Human Receptors to Understand Zoonotic Potential
Mentor(s): Michael Kennedy, Ph.D.
Understanding binding of animal rotavirus strains offers insight into zoonotic potential
The goal of this project is to determine if bat P[10] binds in an excited state to the human glycans that P[II] strains bind
CEST NMR data and 2D 1H-15N-HQSC spectra revealed that L80, T137, G116, and G103 residues may participate in slow confirmational changes of the VP8* receptor binding domain on the VP4 spike protein
